Waterfields attackArmed robbers have struck at another Waterfields bakery, this time in Rainford, Merseyside the seventh raid on the north-west chain in the last few months. Two men demanded access to the safe. Six branches have been hit and bosses do not know what has prompted the spate of attacks.Tesco’s Irish playTesco in Ireland has upped the ante with its ongoing Irish supplier growth initiative, designed to encourage smaller food producers to supply its 130 stores on a regional basis. Earlier this month, the retailer organised its first Irish Food Expo, held in Dublin, where 35 new small suppliers, including a number of bakeries, were signed up. These included Twomeys in Co Limerick and Stapleton’s in Co Tipperary.Roberts gets duckyRoberts Bakery is trialling a new marketing technique after developing an online video, which it hopes will go viral. The new video shows a woman feeding ducks with bread in the park, only for the ducks to throw the bread back at her and chase after a woman carrying a Roberts loaf.New image for ImageGingerbread producer Image on Food has unveiled a new look branding and image, in advance of its silver jubilee celebrations next year.
Harvard Provost Steven E. Hyman announced today (Dec. 16) that Lino Pertile will become director of the Harvard University Center for Italian Renaissance Studies at Villa I Tatti in Florence, Italy, beginning next summer.Pertile will succeed Joseph Connors, professor of history of art and architecture and I Tatti’s sixth director, who has run the center since 2002. After a sabbatical year, Connors will resume teaching, concentrating on Harvard College courses in Italian art.Pertile said of the announcement: “In the 50 years since Bernard Berenson left it to Harvard, Villa I Tatti has had a unique role in the fostering of Renaissance studies, and I am truly honored to be given the opportunity to join this remarkable institution. I look forward with great enthusiasm to carrying on the outstanding work of Joe Connors and the previous directors.”“I am delighted that Lino has accepted the directorship of Villa I Tatti,” said Hyman. “His academic stature, deep knowledge of the Villa, of Italy more broadly, and experience in creating an inclusive scholarly community all make him ideally suited to take the reins of the center and burnish its status as a global leader in Renaissance studies.” He continued, “I look forward to working with Lino in strengthening the ties between Harvard and I Tatti, and developing the center in the years to come.”Pertile, the Carl A. Pescosolido Professor of Romance Languages and Literatures in the Faculty of Arts and Sciences, is a renowned scholar on Italian literature, with a particular focus on the medieval and Renaissance periods. He has taught numerous courses at Harvard College, including, since 1998, the popular “Dante’s Divine Comedy and Its World.”Pertile’s commitment to undergraduate teaching and advising earned him the award of Harvard College Professor in 2005. Since 2000, Pertile has served as master of Eliot House along with his wife, Anna Bensted. Pertile and Bensted are widely credited with creating a warm and welcoming atmosphere at Eliot.Connors said of the announcement: “Lino’s distinguished career as a scholar of Dante and Petrarch — spanning the Italian and Anglo-Saxon worlds of learning — is the true embodiment of what Villa I Tatti is all about, and I couldn’t be more pleased with his appointment. The future of I Tatti under Lino’s leadership looks very bright indeed.”Connors took over I Tatti after serving as chair of the Department of Art History and Archaeology at Columbia University. From 1988 to 1992 he served as director of the American Academy in Rome.“Joseph Connors leaves a superb foundation on which Lino Pertile will continue to build,” said Hyman. “Joe’s model stewardship has transformed the Villa — academically and physically — and he leaves behind a robust center of which Harvard can be proud. We are deeply grateful for his leadership.”Villa I Tatti was founded in 1961 around the house and library of the art critic and connoisseur Bernard Berenson (Class of 1887). It covers 75 acres near Florence, employs a staff of 50, and consists of a fellowship program in Renaissance studies and the Biblioteca Berenson, a research library with distinguished collections in art history, history, literature, and early music, as well as an extensive photographic collection. I Tatti is also known for its historic garden and working farm, and a notable collection of early Italian and Asian art.
An interdisciplinary group of leading Harvard geneticists and stem cell researchers has found a new genetic aspect of cell reprogramming that may ultimately help in the fine-tuning of induced pluripotent stem cells (iPS) into specific cell types.The researchers, who have affiliations with the Harvard Stem Cell Institute (HSCI), the Broad Institute of Harvard and MIT, Harvard’s Department of Stem Cell and Regenerative Biology (SCRB), Children’s Hospital Boston, and Beth Israel Deaconess Medical Center (BIDMC), have identified a set of genetic elements never before known to be involved in cellular reprogramming.According to John Rinn, a corresponding author of the study who is affiliated with HSCI, SCRB, the Broad, and BIDMC, “this is the first time that this new type of gene has been implicated in the reprogramming process. In reprogramming it’s important to find as many routes to reprogramming as possible. This finding gives us another set of fingers to play on the genomic piano that controls the ‘music’ of cellular reprogramming.”“This is a group of RNAs that come from the dark region of the genome,” Rinn said. “We don’t know everything they do, but they clearly are involved in the reprogramming process.”“We know reprogramming resets the genome [of the reprogrammed cell] globally,” said George Daley of HSCI and Children’s Hospital and, along with Rinn, one of the two senior authors of a paper published online by Nature Genetics. “What we’ve learned by working with John is that lincRNAs play essential roles in the reprogramming process. We’ve even identified one lincRNA that enhances reprogramming, which is tantalizing evidence that we can make reprogramming more efficient by harnessing lincRNAs.”Added Daley, a biologist, “our groups came together to answer a question that neither group could answer alone.”The new finding follows by less than two months the discovery by HSCI’s Derrick Rossi and colleagues that skin cells could be returned to an embryonic stem cell-like state using specially engineered synthetic mRNAs, eliminating the need to use viruses that can induce cancers to develop.Rossi’s discovery turned the cell reprogramming field on its head, and was considered so significant that HSCI co-director Doug Melton announced that the HSCI iPS core, which produces reprogrammed cells for researchers, would immediately switch to using the method developed by Rossi.The new findings by Rinn, Daley, and colleagues may help explain why Rossi’s method works — because RNAs appear to be part of the natural cell programming process — and may also be used to refine the Rossi reprogramming method, Rinn said. “What we think we’ve done is, [we’ve found] another way to throw the reprogramming switches,” Rinn said.The road to this latest discovery began when Rinn first arrived at Harvard and the Broad in January 2009. He, Broad director Eric Lander, and Mitch Guttman, who are also authors on the Nature Genetics paper, discovered a group of 5,000 lincRNAs. “Then we worked with George (Daley) to figure out their relevance, if any, in reprogramming,” Rinn said.Like much of scientific discovery, the latest finding was serendipitous. As Rinn explains it:“We started out looking for something else: We wanted to know what happens when you program skin cells that originate in different parts of the body into stem cells. George and I were on a committee meeting together with a student who didn’t know the anatomic origin of the skin cells used to make stem cells. A light bulb went off that it may be interesting to make stem cells from skin cells originating all around the body and see if they ‘remember’ where they came from. Sabine Loewer, the lead author on the paper, immediately jumped at the idea as well — which was very brave for such a risky project.“It turned out they didn’t matter where the cells came from,” Rinn said, “which is in itself an important finding. But in the process we found that hundreds of lincRNA genes were turned on and off during the reprogramming, so we focused on the ones that turned on, to see if they were part of the pluripotency process, and they were.”
Comment The Brazilian centre-back likes what he saw from the January recruit (Picture: Getty)David Luiz has praised ‘amazing’ Pablo Mari after the Spanish centre-back impressed on his Arsenal debut in the FA Cup against Portsmouth on Monday night.Mari, who moved to the Emirates in January from Brazilian club Flamengo, has been made to wait to get his chance in the Arsenal first-team, not making a matchday squad since he joined the Gunners.But he was picked to start against Portsmouth in the 2-0 FA Cup fifth round win, partnering Luiz in the heart of the defence, and the Brazilian has been impressed with his new teammate. Luiz and Mari lined up in the centre of defence while Sokratis was at right-back (Picture: Getty)Asked about the young Arsenal side’s clean sheet, and Mari’s debut, Luiz told BT Sport after the game: ‘It’s great, these kind of things we have to learn.AdvertisementAdvertisementADVERTISEMENT‘I think we did great tonight, everybody was 100 per cent focused and we didn’t concede. I’m so happy for Pablo, he’s a great guy.‘A great player and he had an amazing game so we are here to help each other and we are here, 25 players, ready to play, ready to play for Arsenal and ready to give the best job.More: Arsenal FCArsenal flop Denis Suarez delivers verdict on Thomas Partey and Lucas Torreira movesThomas Partey debut? Ian Wright picks his Arsenal starting XI vs Manchester CityArsene Wenger explains why Mikel Arteta is ‘lucky’ to be managing Arsenal‘When it’s like that it’s a pleasure to play football as I will say to the guys, especially to these young lads who are starting football.‘They are starting with a great opportunity at a big club and they are doing great, so it’s a pleasure to play with them.’ Metro Sport ReporterTuesday 3 Mar 2020 8:45 amShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link8.2kShares Advertisement Goals from Sokratis and Eddie Nketiah either side of half-time secured Arsenal’s win (Getty)Arsenal boss Mikel Arteta also spoke about Mari’s debut, saying: ‘I think he looked comfortable.‘He is very vocal and very comfortable on the ball, always commanding the back four and he looked like he’s played here for months. I think we have a good player.’MORE: Mikel Arteta rates Pablo Mari’s debut for Arsenal against PortsmouthMORE: Sokratis was moaning about playing right-back in Arsenal win over Portsmouth, admits Mikel ArtetaFollow Metro Sport across our social channels, on Facebook, Twitter and Instagram.For more stories like this, check our sport page.More: FootballRio Ferdinand urges Ole Gunnar Solskjaer to drop Manchester United starChelsea defender Fikayo Tomori reveals why he made U-turn over transfer deadline day moveMikel Arteta rates Thomas Partey’s chances of making his Arsenal debut vs Man City David Luiz praises debutant Pablo Mari after performance in Arsenal’s FA Cup win Advertisement
FOOTBALL action in the 2017 Limacol round-robin knock-out received a boost yesterday when the proprietor of Trophy Stall, Ramesh Sunich, donated the first-place trophy and goal nets.The Petra-organised tournament begins on January 23. Sunich praised the organising body for the efforts to elevate the sport, hence his donation to the cause.Receiving the trophy, co-Director of Petra Organisation, Troy Mendonca, added that the tournament helps to showcase the talent in teams that are not in the elite, with the aim of allowing them to hopefully elevate themselves in the future.Meanwhile the tournament’s first playing date is January 23 with Group D action when Police play Mahaica and Riddim Squad oppose Camptown. Both games will be played at the GFC ground, Bourda.Action returns on January 27 when Group B’s Western Tigers play New Amsterdam United at GFC and Group C’s Santos oppose Ann’s Grove.The following evening will see action at the Mackenzie Sports Club ground as Milerock play Northern Rangers and Winners Connection play Grove HiTech in Group A.
FANTASY: Start ’em/sit ’em advice for Week 12 Brady, 42, has displayed legendary durability throughout his career. He has started all 10 of New England’s games this season, and aside from 2016, when he was suspended by the NFL for the first four games for his role in Deflategate, and 2008, when he suffered season-ending knee injury in Week 1, he has started all 16 games every year from 2002-18. He started 14 of 14 games after taking over for an injured Drew Bledsoe as the No. 1 QB in Week 3 of the 2001 season. The Patriots head into the weekend with a possible concern about quarterback Tom Brady.New England listed Brady (elbow) as questionable for its late-afternoon game Sunday vs. the Cowboys, but NFL Network’s Ian Rapoport reported that Brady is expected to play. Brady was a limited participant in Friday’s practice, the team said. If Brady cannot go Sunday, then rookie Jarrett Stidham would take over. Stidham, 23, has thrown four passes, completing two, this year. He also has thrown an interception, which the Jets’ Jamal Adams returned for a touchdown.Brady has led the Patriots to a 9-1 record, but several of his key numbers are down compared to recent years. His completion percentage (63.7), yards per attempt (7.0) and passer rating (90.7) are all at their lowest since the 2013 season.New England leads the AFC East by two games over the Bills and also have a head-to-head tiebreaker over Buffalo.